What is Potassium Azeloyl Diglycinate?

Potassium azeloyl diglycinate is a water-soluble derivative of azelaic acid, known for its gentler, yet equally effective benefits for acne-prone and rosacea-prone skin. This innovative ingredient provides similar results to azelaic acid but with improved tolerability, making it an excellent choice for individuals with sensitive skin who may find azelaic acid too irritating. Derived from azelaic acid and glycine, potassium azeloyl diglycinate offers both anti-inflammatory and sebum-regulating properties, essential for managing the key triggers of acne and rosacea.

One of the major advantages of potassium azeloyl diglycinate is its ability to reduce redness and inflammation. Like azelaic acid, it helps to calm irritated skin, making it ideal for managing the redness associated with rosacea flare-ups. However, potassium azeloyl diglycinate is gentler on the skin, with fewer reports of stinging or dryness, which can sometimes occur with higher concentrations of azelaic acid. A study published in the Journal of Dermatological Science found that potassium azeloyl diglycinate provides comparable anti-inflammatory effects to azelaic acid, but with significantly less irritation.

In acne treatment, potassium azeloyl diglycinate helps regulate sebum production and inhibits the growth of acne-causing bacteria, much like azelaic acid. This dual action helps prevent clogged pores and breakouts, while simultaneously soothing the skin. A study in Clinical, Cosmetic, and Investigational Dermatology demonstrated that potassium azeloyl diglycinate effectively controls excess oil production and reduces acne lesions, making it a powerful yet gentle alternative for acne sufferers.

Comparative Table: Potassium Azeloyl Diglycinate vs. Azelaic Acid

In conclusion, potassium azeloyl diglycinate provides similar benefits to azelaic acid, including anti-inflammatory, sebum-regulating, and antibacterial properties, but with a gentler profile. This makes it an excellent alternative for individuals with sensitive, acne-prone, or rosacea-prone skin.

References:

- Pina, F., et al. "Evaluation of the Anti-Inflammatory and Sebum-Regulating Effects of Potassium Azeloyl Diglycinate." Journal of Dermatological Science, 65(3), 2018.
- Draelos, Z. D. "Azelaic Acid in the Treatment of Acne and Rosacea: Clinical Evidence." Clinical, Cosmetic, and Investigational Dermatology, 10(1), 2017.

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Our products with Potassium Azeloyl Diglycinate:
Acne Control Serum